Reaction Biology Corp. Awarded NIH SBIR Grant for Kinase Radioisotope Microarray Screening Development

| From


MALVERN, Pa., June 20 (SEND2PRESS NEWSWIRE) -- Reaction Biology Corporation ("RBC") today announced that it has been awarded an SBIR grant from the National Cancer Institute to create a new kinase profiling and high throughput screening method using radioisotopes and microarrays. The $940,000 grant will be used to migrate the current well-plate radioisotope methods onto RBC's DiscoveryDot(TM) nanoliter screening platform.

Protein kinase dysfunction is a key factor in cancer, inflammation and diabetes. Screening and profiling kinase inhibitors has been a major research and development effort in the pharmaceutical industry. While screening kinase activity with radioisotope detection is considered by many in the drug-discovery industry to be the "gold standard" of kinase assays, use of the format is limited by expense and the difficulty of radioactive disposal.

The DiscoveryDot(TM) platform uses only a fraction of the reagents compared to well plate methods. "Due to our nano-scale format, the amount of radioisotope used in the process should be minimal," said RBC Chief Technology Officer Haiching Ma, Ph.D. "This should lead to far fewer disposal and handling problems, and reduced cost overall."

About Reaction Biology Corporation

Reaction Biology, based in Malvern, Pa., provides high throughput screening services to the biotechnology and pharmaceutical industries. The company uses a patent-pending combination of technologies to perform screening at the nanoliter scale, while preserving quality, speed and simplicity. Combining genomics microarray printing technology and picoliter aerosol deposition, RBC has commercialized a novel technology that drives HTS to new levels of simplicity and efficiency.

More information:

News Source:
Like, Share, Save this press release:
  TWEET   SHARE   G+   STUMBLE   LinkedIn   Instapaper   Buffer

The content of the above press release was provided by the “news source” (Reaction Biology Corporation) or authorized agency, who is solely responsible for its accuracy. Send2Press® is the originating wire service for this story and content is Copr. © 2006 Reaction Biology Corporation with newswire version Copr. © 2006 Send2Press (a service of Neotrope). All trademarks acknowledged.

Rights granted for reproduction by any legitimate news organization. However, if news is cloned/scraped verbatim, then original attribution must be maintained with link back to this page as “original syndication source.” Resale of this content for commercial purposes is prohibited without a license. Reproduction on any site selling a competitive service is also prohibited. Information is believed accurate, as provided by news source or authorized agency, however is not guaranteed, and you assume all risk for use of any information found herein/hereupon. This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License.
STORY READS for this single page only, as of Oct 28 2016:
[ count retired 8.4.16 ]

back to top
REFERENCES: Reaction Biology , DiscoveryDot, DiscoveryDot nanoliter screening platform, RBC, genomics microarray printing technology and picoliter aerosol deposition, Reaction, Biology, Corporation, Haiching Ma, news, press release from Reaction Biology Corporation, Jun 20, 2006, Biotechnology, Pharma, , , , Reaction Biology Corp. Awarded NIH SBIR Grant for Kinase Radioisotope Microarray Screening Development